Moc 6415a updating your
I have previously worked in the Physics department at the University of California, Santa Barbara, CA, USA; University of St.Andrews, Scotland, UK; and Lund University, Lund, Sweden.
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Thrombus formation over a ruptured atherosclerotic plaque cap can occlude an artery with fatal consequences.
We describe a computational model of platelet transport and binding to interpret rate-limiting steps seen in experimental thrombus formation over a collagen-coated stenosis.
Adhesion is modeled as platelet-platelet binding kinetics.
The results indicate that observed thrombus growth rates are limited by platelet transport to the wall for shear rates up to 6000 s(-1).
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From August 1995 to January 1997, therapy with topical clobetasol propionate in combination with chloroquine sulfate and then hydroxychloroquine sulfate was ineffective.